Induced Effects Of Genotoxic Agents In Eukaryotic CellsToby G Rossman CRC Press, 21 thg 9, 1992 - 167 trang This book provides an understanding of the consequences of induced proteins in the toxicological response of cells to chemical and radiation damage to DNA and will be helpful in creating proper mathematical models for extrapolation to low doses and assessing human exposure or cellular injury. |
Nội dung
Induction of a UV DamageSpecific DNABinding Protein | 21 |
CellCycle and DNADamage Regulation | 65 |
Gene AmplificationA Cellular Response | 81 |
CarcinogenInducible Proteins as Mediators | 97 |
CarcinogenInduced Gene Amplification and Gene | 113 |
gadd153 a Growth Arrest and DNA Damage Inducible | 125 |
Ultraviolet Irradiation and Phorbol Esters Induce Gene | 141 |
| 163 | |
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Thuật ngữ và cụm từ thông dụng
Acad alkylating assay binding Biochem Biol c-fos c-jun Cancer Res carcinogen-induced carcinogen-treated Carcinogenesis carcinogens cDNA cell cycle cell lines cellular Chinese hamster cloned collagenase DHFR DNA damage DNA ligase DNA repair DNA replication DNA sequences DNA synthesis DNA-damaging agents doses early domain element Elledge and Davis encoding enhanced enzyme eukaryotic extracts fibroblasts Fornace gene amplification gene expression genetic genome GST Ya gene Herrlich human cells identified increase inducible genes inhibition inhibitors irradiation J/m² Laval Lavi ligase activity Lücke-Huhle mammalian cells Mezzina molecular mouse mRNA mutations Natl oligonucleotide Oncogene pathways phorbol ester plasmid polyoma Proc promoter protein kinase radiation Rahmsdorf receptor region regulatory response to DNA ribonucleotide reductase RNR1 RNR2 RNR3 role Ronai signal simian virus 40 specific Stein SV40 amplification tion transcription factors transfected transferase treated treatment UV-DDB protein UV-induced UV-irradiated viral DNA vitro xenobiotic yeast µg/ml
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Trang 139 - Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation. Proc. Natl. Acad. Sci. USA 86:10104-7 37.