Research in Computational Molecular Biology: 12th Annual International Conference, RECOMB 2008, Singapore, March 30 - April 2, 2008, Proceedings

B́a trước
Martin Vingron, Limsoon Wong
Springer Science & Business Media, 14 thg 3, 2008 - 480 trang

This book constitutes the refereed proceedings of the 12th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2008. It presents current issues in algorithmic, theoretical, and experimental bioinformatics.

 

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Its Challenges Past Present and Future
1
Unsupervised Identification of Protein Complexes in Yeast
3
A DNA CompositionBased Algorithm for Binning Environmental Shotgun Reads
17
Reconstructing the Evolutionary History of Complex Human Gene Clusters
29
Ab Initio Whole Genome Shotgun Assembly with Mated Short Reads
50
Orchestration of DNA Methylation
65
A Bayesian Hierarchical HMM for CisRegulatory Module Decoding in Metazoan Genomes
66
A Combined ExpressionInteraction Model for Inferring the Temporal Activity of Transcription Factors
82
HighResolution Modeling of Cellular Signaling Networks
257
How Did Folded Proteins Evolve?
272
Locating Multiple Gene Duplications through Reconciled Trees
273
Rapid and Accurate Protein Side Chain Prediction with Local Backbone Information
285
Algorithms for Joint Optimization of Stability and Diversity in Planning Combinatorial Libraries of Chimeric Proteins
300
DLIGHT Lateral Gene Transfer Detection Using Pairwise Evolutionary Distances in a Statistical Framework
315
Computation of Median Gene Clusters
331
From Translocation to Therapy
346

A Fast AlignmentFree ConservationBased Method for Transcription Factor Binding Site Discovery
98
The Statistical Power of Phylogenetic Motif Models
112
Transcriptional Regulation and Cancer Genomics
127
Automatic Recognition of Cells ARC for 3D Images of C elegans
128
Using Multiple Mass Spectra for De Novo Peptide Sequencing
140
A Fragmentation Event Model for Peptide Identification by Mass Spectrometry
154
A Bayesian Approach to Protein Inference Problem in Shotgun Proteomics
167
De Novo Sequencing of Nonribosomal Peptides
181
Systems Metabolic Engineering
196
Protein Function Prediction Based on Patterns in Biological Networks
197
Automatic Parameter Learning for Multiple Network Alignment
214
An Integrative Network Approach to Map the Transcriptome to the Phenome
232
Fast and Accurate Alignment of Multiple Protein Networks
246
Detecting DiseaseSpecific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
347
Constructing Treatment Portfolios Using Affinity Propagation
360
Alternative Splicing Events of Arbitrary Dimension in Splicing Graphs
372
More Efficient Algorithms for Closest String and Substring Problems
396
Disruption of a Transcriptional Regulatory Pathway Contributes to Phenotypes in Carriers of Ataxia Telangiectasia
410
Accounting for Nongenetic Factors Improves the Power of eQTL Studies
411
Effects of Genetic Divergence in Identifying Ancestral Origin Using HAPAA
423
Increasing Power in Association Studies by Using Linkage Disequilibrium Structure and Molecular Function as Prior Information
434
Panel Construction for Mapping in Admixed Populations Via Expected Mutual Information
435
Constructing Level2 Phylogenetic Networks from Triplets
450
Accurate Computation of Likelihoods in the Coalescent with Recombination Via Parsimony
463
Author Index
478
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