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APPENDIX, No. 4.-A return of members of the House of Commons holding offices for a term of years under grant from the crown, or other public officers :—

Pennant, George Hay Dawkins, bailiff of the hundred

of Uchef, in Carmarthenshire.

15 9 1

APPENDIX, No. 5.-A return of members of the House of Commons holding offices for life under appointments from the chiefs in the courts of justice.

Courtenay, William, master in chancery

3,600 0 0

And office of writs and subpoenas.

Dowdeswell, John Edmund, master in chancery

2,698 9 0

Fitz. Gibbon, hon. Richard, usher and registrer of affi

davits, court of chancery in Ireland.

3,534 12 0

Wrottesley, Henry, cursitor for Lincoln and Somerset, duty executed by deputy

197 0 0

APPENDIX, No. 6.—A return of all pensions or sinecures, or offices chiefly executed by deputy, held by members of the House of Commons under grants from the crown, or by act of parliament:Bentinck, lord William Henry Cavendish, clerk of the

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A lieut.-general and colonel of the 11th Dragoons.
Jocelyn, hon. John, superannuation allowance on the
Irish establishment
Morland, sir Scrope Bernard, bart., two annuities on
44 per cent duties, 3001. each.

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Pechell, sir Thomas Brooke, bart., servant of her late
majesty, and a major-general in the army
Villiers, right hon. John Charles, warden and chief
justice of Eyre North of Trent, and clerk or protho-
notary of pleas at Lancaster, by letters patent.

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1,150 0 0

650 0 0

600 0 0

200 0 0

4,878 0 0

APPENDIX, No. 7.-A return of members of the House of Commons holding the reversion of offices under the crown, after one or more lives; stating the office and nett proceeds at present of such office :

Jenkinson, hon. Charles Cecil Hope, reversion of office of clerk of pleas, Lancaster

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Wellesley, Richard, reversion of office chief remembrancer of the court of exchequer in Ireland

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The appendix No. 8, consisting of "a return of officers on the full and half pay of the army and navy, the militia and yeomanry not included," is of considerable length, but merely names the commissions, without detailing the profits derived from them.

REPORT from the NATIONAL VACCINE ESTABLISHMENT.

To the Right Hon. Robert Peel,
principal Secretary of State for
the Home Department.

National Vaccine Establishment,
Percy street, Jan. 31.

SIR, Vaccination has now been submitted to the test of another year's experience, and the result is an increase of our confidence in the benefits of it. We are happy to say that it appears to have been practised more extensively than it was, notwithstanding the influence of exaggerated rumours of the frequent occurrence of smallpox subsequently, on the minds of some persons, and the obstinate prejudices of others, who still continue to adopt inoculation for that disease. The unavoidable consequence of the latter practice is, to supply a constant source of infection, and to put the merits of vaccination perpetually to the severest trial.

Of small-pox, in the modified and peculiar form which it assumes when it attacks a patient who has been previously vaccinated, many cases indeed have been reported to us in the course of last year, and some have fallen within the sphere of our own observation; but the disorder has always ran a safe course, being uniformly exempt from the secondary fever, in which the patient dies most commonly, when he dies of small-pox.

For the truth of this assertion, we appeal to the testimony of the whole medical world; and for a proof that the number of such cases bears no proportion to the thousands who have profited to the fullest extent of security, by its protecting influence, we appeal VOL. LXIV.

confidently to all who frequent the theatres and crowded assemblies, to admit that they do not discover in the rising generation any longer that disfigurement of the human face, which was obvious every where some years since.

To account for occasional failures, of which we readily admit the existence, something is to be attributed to those anomalies which prevail throughout nature, and which the physician observes, not in some peculiar constitutions only, but in the same constitution at different periods of life, rendering the human frame at one time susceptible of disorder from a mere change of the wind, and capable, at another, of resisting the most malignant and subtle contagion. But amongst the most frequent sources of failure which have occurred, and will for a time continue to occur, is to be numbered that careless facility with which unskilful benevolence undertook to perform vaccination in the early years of the discovery; for experience has taught us, that a strict inquiry into the condition of the patient to be vaccinated, great attention to the state of the matter to be inserted, and a vigilant observation of the progress of the vesicles on the part of the operator, are all essentially necessary to its complete success.

That less enlightened parents should hesitate to accept a substitute for inoculation, which is not perfect in all its pretensions, and absolutely and altogether effectual to exempt the objects of their solicitude from every future possible inconvenience, does not surprise 2 L

us; but we cannot forbear to ex-
press our unqualified reprobation
of the conduct of those medical
practitioners, who, knowing well,
that vaccination scarcely occasions
the slightest indisposition, that it
spreads no contagion, that in a very
large proportion of cases it affords
an entire security against small-
pox, and in almost every instance
is a protection against danger from
that disease, are yet hardy enough
to persevere in recommending the
insertion of a poison, of which
they cannot pretend to anticipate
either the measure or the issue
(for no discernment is able to dis-
tinguish those constitutions which
will admit inoculated small-pox
with safety), and there are some
families so dangerously affected by
all the eruptive diseases, that they
fall into imminent hazard in tak-
ing any of them. This remark
has a particular application to
small-pox. A family lost its two
first-born children of the small-pox,
inoculated by two of the most skil-
ful surgeons of the time; nor is it
improbable that the parents might
have had to lament the loss of
more children, under the same for-
midable disease, if the promulga-
tion of the protecting influence of
vaccination had not happily inter-
posed to rescue them from the con-
sequences of a repetition of the
fatal experiment. Of their re-
maining children, one took the
small-pox after vaccination, and
went through it in that mild and
mitigated form which stamps a
value
upon this resource, as real in

the eye
of reason and sound philo-
sophy, as when it prevents the ma-
lady altogether.

We have contended sir, for this its merits, with all the powers of our understanding, and with all that just and fair pretension to con

vince others, to which we are en"
titled by being firmly and sincerely
Nor shall
convinced ourselves.
we relax in our efforts to promote
its adoption, but continue to exert
the influence which the benevolent
designs of parliament, in establish-
ing this board, have given us for
extending the benefits of this salu-
tary practice.

it

That the blessing is not yet ab solutely perfect, we are ready to admit; but when we compare with inoculation for the small-pos, the only alternative, we have no hesitation in stating, that the com parison affords an irresistible proof of its superior claims to regard; for we learn from ample experience that the number of cases of smallpox, in the safe form which it is found to assume after vaccination, is by no means equal to the num ber of deaths by inoculation; evidence quite irrefragable, and, as it appears to us, decisive as to the incalculable advantages of the pra tice of the first over that of the latter method.

who The number of persons have died of small-pox this year within the bills of mortality is only 508; not more than twothirds of the number who fell a sacrifice to that disease the year before; and as in our last report we had the satisfaction of stating that more persons had been vacci nated during the preceding than any former twelve months, flatter ourselves that this diminu tion of the number of deaths from

We

small-pox may fairly be attributed to the wider diffusion of vaccination (Signed)

the Royal

HENRY HALFORD, President
ALGN. FRAMPTON,) Censors
THO. HUME,
CHAS. BADHAM,
ROBERT LLOYD,

College of

Physicians

EVERARD HOME, (Master of the Royal College of Surgeons.)

WILLIAM BLIZARD, &

HENRY CLINE, (Governors of

the Royal College of Sur-
geons.)

By order of the Board,
JAMES HERVEY, M. D.
Registrar.

SUBSTANCE of the 16th REPORT of the AFRICAN INSTITUTION.

This report states, that from the information which has reached the institution from unquestionable sources, and especially from papers laid before parliament,

It appears, that the whole line of Western Africa, from the river Senegal to Benguela-that is to say, from the latitude of about 15 deg. north, to the latitude of about 13 deg. south-has, during that period swarmed with slave vessels, and that an active and increasing slave trade has also been carried on upon the eastern shores of that continent, particularly from the island of Zanzebar.

The chief seat of this detestable traffic on the west coast may be considered to be the rivers Bonny and Calabar. It was ascertained on good authority, by captain Leeke, of his majesty's ship Myrmidon, that from July, 1820, to October, 1821, an interval of about 15 months, 190 slave ships had entered the former river, and that 162 had entered the latter, for the purpose of purchasing slaves-a fact which may afford some idea of what must have been the dreadful aggregate of misery inflicted during the last year on that unhappy portion of the globe.

The report then takes a view of the state of the slave trade under the different heads connected with the subject, commencing with

PORTUGAL.

In this work of iniquity and devastation Portugal still takes a prominent part; Portugal, it will be recollected, is the only European power that has refused entirely to prohibit her subjects from trading in slaves. She retains the guilty distinction of still legalizing a traffic which she acknowledges at the same time to be a crime of the worst description. She engaged, it is true, at the congress of Vienna, to limit her slave trade to her own possessions south of the equator; and she held out a qualified expectation, that in the year 1823 it should cease every where, and for ever. Her restrictive stipulations, however, have been attended with little benefit to Northern Africa, for they have continued to be most grossly and extensively violated by her subjects; some even of her public functionaries, governors of African colonies, have not scrupled by their own practice, openly to sanction the violation, and to set at nought the laws they were bound to execute.

An active slave trade has been unceasingly carried on between the adjoining continent and the islands of Bissao and Cape de Verd. These islands are used as dépôts for the slaves taken thither in canoes and

small vessels, by French and other slave traders, with the view of being afterwards removed to the Havannah or to the French West India islands. But it is to the rivers which run into the Bight of Benin, and into that of Biafra, that the Portuguese slave ships chiefly resort. Many such vessels, in the course of the last year, have been found there by his majesty's ships, completely furnished with all the implements of their criminal traffic, and in a state of readiness to embark their human cargo. The traffic, however, has been but in a slight degree checked by being discovered; for as it is only when slaves have actually been embarked, that they can be seized by British cruizers, the persons engaged in the trade often take no pains to conceal the purpose of their voyage; on the contrary, they seem to exult in the mortification, to which our naval officers are subjected in a great number of instances, of being obliged by the terms of the conventions to leave them unmolested.

slaves, have been seized in the course of the last year, and condemned by the mixed commission

courts.

The directors are happy to per ceive that Portugal, as well as Spain and the Netherlands, has acceded to an important amendment in the terms of the convention for repressing the slave trade, which is comprised in the following additional article, viz.

"It is agreed, that if there shall be clear and undeniable proof, that a slave or slaves have been, for the purpose of illegal traffic, put on board a vessel in the immediate cruise on which the vessel shall be captured, then and on that account according to the true intent and meaning of the stipulations of the treaty of the 22nd day of January, 1815, and of the additional c vention of the 28th day of July, 1817, she is to be justly detained by cruisers, and finally condemned by the commissioners, although such slave or slaves shall not be found actually on board at the time of capture.

"The present additional article shall have the same force and ef fect as if it were inserted, word for word, in the additional Con vention of the 28th day of July, 1817."

The ordinary course of proceeding, adopted not only by the Portuguese but by all the other slave traders (excepting the French, who alone pursue their trade without risk of capture), is to keep the slaves, whom they purchase, on At the congress of Vienna, & shore, until the very day on which has already been remarked, Port they may deem it safe to commence gal held out some hope that in their voyage; and when they 1823 she would entirely abolish have ascertained that there are no her slave trade. That hope, it is cruisers in the way to obstruct greatly to be feared, will prove al their passage, they embark their together delusive, as no step ap cargo and depart forthwith to their pears yet to have been taken to destined place of sale. Such, how- realize it, and as every application to that effect on the part of Great Igaged in this guilty commerce, Britain, has hitherto been eluded that, notwithstanding the facilities by the Portuguese government. of escape thus afforded them, several Portuguese ships, loaded with

ever, is the number of vessels en

the congress of Vienna had fore The chief contracting powers at

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